Name : RAT ANTI MOUSE PLVAP:FITC Antibody
Supplier : MBS MONO
Price :343
SKU : GEN9285128013
| Also known as | PLVAP |
| Other names | MECA-32 antigen, MECA-32 antigen, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein, plasmalemma vesicle associated protein, plasmalemma vesicle protein 1, plasmalemma vesicle-associated protein, plasmalemma vesicle-associated protein |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | PLVAP |
| Gene name synonims | N/A |
| Other gene names | MECA32, PV-1, Plvap, Pv1, Pv1, Plvap |
| Clonality | Monoclonal |
| Immunoglobulin isotype | IgG2a |
| Clone | MECA-32 |
| Host organism | Rat (Rattus norvegicus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity | In adult and embryonic mice, In embryonic mice, PLVAP expression, PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_In humans, a 60kD protein which is otherwise known as MECA-32 and PV-1, as well as other cerebral disorders associated with blood-brain barrier disruption, cardiac and brain tissues, including glioblastoma and metastatic carcinoma, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated, such as acute ischemia, PLVAP This item recognises murine plasmalemma vesicle-associated protein (PLVAP) |
| Purification method | N/A |
| Form/Appearance | FITC (Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid) |
| Concentration | 1 miligram per 1 mililiter, IgG concentration 0 |
| Storage and shipping | If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Storage in frost-free freezers is not recommended, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications: | Flow Cytometry (FACS) |
| Properties | FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Conjugation | Anti-FITC Antibody |
| Gene target | PLVAP: |
| Short name | RAT ANTI MOUSE PLVAP:FITC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, Antibody |
| Label | FITC |
| Alternative name | RAT antibody to MOUSE PLVAP:fluorecein (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13635 |
| Gene | PLVAP |
| Long gene name | plasmalemma vesicle associated protein |
| Synonyms | gp68 PV-1 PV1 FELS |
| Synonyms name | PV-1 protein , fenestrated-endothelial linked structure protein |
| Locus | 19p13, 11 |
| Discovery year | 2001-04-27 |
| GenBank acession | AF326591 |
| Entrez gene record | 83483 |
| Pubmed identfication | 11401446 |
| RefSeq identity | NM_031310 |
| Havana BLAST/BLAT | OTTHUMG00000182784 |