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RAT ANTI MOUSE TIM-4:RPE Antibody

RAT ANTI MOUSE TIM-4:RPE Antibody size: 25 Tests 382

Supplier MBS MONO
Price 382
Size 25 Tests
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asTIM-4
Other names SMUCKLER, Spleen, T cell immunoglobulin and mucin domain containing 4, T-cell immunoglobulin and mucin domain containing 4, T-cell immunoglobulin and mucin domain-containing protein 4, T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, T-cell membrane protein 4, TIM-4, TIMD-4, knockout of lymphotoxin protein, knockout of lymphotoxin protein, mucin-containing, mucin-containing, smuckler, spleen, T-cell immunoglobulin and mucin domain-containing protein 4
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameTIM-4
Gene name synonimsN/A
Other gene names B430010N18Rik, SMUCKLER, TIM-4, TIMD-4, Tim4, Tim4, Timd4, Timd4
ClonalityMonoclonal
Immunoglobulin isotypeIgG2a
CloneRMT4-54
Host organismRat (Rattus norvegicus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus)
Specificity and cross-reactivity Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The TIM-4 gene locus is associated with predisposition to asthma in both mice and humans and may be considered as a candidate disease gene for asthma, This particular antibody might cross react with speacies outside of the listed ones, _x000D__x000D_Studies have shown that clone RMT4-54 significantly inhibits the efficient phagocytosis of apoptotic cells by PRMs (peritoneal resident Mac1<, _x000D__x000D_Tim-4 is reported to be crucial for the phagocytosis of apoptotic cells by peritoneal macrophages, a transmembrane glycoprotein and member of the immunoglobulin superfamily, and studies have shown that interaction between Tim-1 on Th2 cells and Tim-4 on DCs, but not PEMs (peritoneal exudate Mac1<, cells), cells), enhances Th2 cell function, exclusively expressed by antigen-presenting cells, involved in T-cell expansion and cytokine production, which acts as the natural ligand of Tim-1, +<, +<, /sup>, /sup>, TIM-4 Clone RMT4-54 specifically recognises mouse Tim-4 (T-cell immunoglobulin mucin 4), sup>, sup>
Purification methodN/A
Form/Appearance Phycoerythrin (RPE) - liquid), RPE (Purified IgG conjugated to R
ConcentrationN/A
Storage and shipping DO NOT FREEZE, If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Shelf Life: 12 months from date of dispatch, Temperature variations in the range between +1C to +7C are tolerable, the antibody is photosensitive and should be protected from light, the antibody should be stored undiluted, Keep the antibody refrigerated at +4 degrees Celsius
Tested applications:Flow Cytometry (FACS)
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°
Gene targetTIM-4:RPE
Short nameRAT ANTI MOUSE TIM-4:RPE Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAT antibody to MOUSE TIM-4:RPE (Antibody to)
Alternative techniqueantibodies

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