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Rb/P105 RB (Ser807 + Ser811) Antibody

Rb/P105 RB (Ser807 + Ser811) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRb/P105 RB (Ser807 + Ser811) Antibody
Also known asRb/P105 RB (Ser807 + Ser811) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRb/P105 RB Ser807 + Ser811
SpecificityThis is a highly specific antibody against Rb/P105 RB Ser807 + Ser811
Modification(s)Phosphorylation
Modification site(s)Ser807 + Ser811
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human P105 RB around the phosphorylation site of Ser807/Ser811
Gene ID number5925
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Nuclear MarkerRb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Including osteosarcoma, OSRC, P105 RB, P105RB, PP105, PP110, RB 1, RB1, RB1 protein, RB_HUMAN, Retinoblastoma 1, Retinoblastoma 1 including osteosarcoma, Retinoblastoma associated protein, Retinoblastoma related osteosarcoma, Retinoblastoma susceptibility gene, pRb, RbSer807
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRb/P105 RB (Ser807 + Ser811)
Short nameRb/P105 RB (Ser807 + Ser811) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRb/P105 RB (Ser807 and Ser811) (Antibody to)
Alternative techniqueantibodies
Identity 7795
Gene NFKB2
Long gene name nuclear factor kappa B subunit 2
Synonyms gene name nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Synonyms LYT-10 p52 p105 NF-kB2 p49/p100
Locus 10q24, 32
Discovery year 1991-11-14
GenBank acession X61498
Entrez gene record 4791
Pubmed identfication 1876189
Classification Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT OTTHUMG00000018962

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