Filters

Rb/P105 RB (Ser807 + Ser811) Antibody, ALEXA FLUOR 647

Rb/P105 RB (Ser807 + Ser811) Antibody, ALEXA FLUOR 647 size: 100ul 350

Price 350
Size 100ul
Long name ALEXA FLUOR 647 Conjugated, Rb/P105 RB (Ser807 + Ser811) Antibody
Also known asAnti-Rb/P105 RB Ser807 + Ser811 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRb/P105 RB Ser807 + Ser811
SpecificityThis is a highly specific antibody against Rb/P105 RB Ser807 + Ser811
ModificationPhosphorylation
Modification SiteSer807 + Ser811
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human P105 RB around the phosphorylation site of Ser807/Ser811
Gene ID Number5925
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Nuclear MarkerRb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms LYT-10 p52 p105 NF-kB2 p49/p100
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Rb/P105 RB (Ser807 + Ser811) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetRb/P105 RB (Ser807 + Ser811)
Short nameRb/P105 RB (Ser807 + Ser811) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, Rb/P105 RB (Ser807 and Ser811) (Antibody to)
Alternative techniqueantibodies
Identity 7795
Gene NFKB2
Long gene name nuclear factor kappa B subunit 2
Synonyms gene name nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Locus 10q24, 32
Discovery year 1991-11-14
GenBank acession X61498
Entrez gene record 4791
Pubmed identfication 1876189
Classification Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT OTTHUMG00000018962

Subscribe to our Newsletter