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RCC1 (Ser11) Antibody, FITC Conjugated

RCC1 (Ser11) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, RCC1 (Ser11) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRCC1 Ser11
SpecificityThis is a highly specific antibody against RCC1 Ser11
ModificationPhosphorylation
Modification siteSer11
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RCC1 around the phosphorylation site of Ser11
Gene ID number1104
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background RCC1, RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin, and, but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, to increase the affinity of chromatin for NE membranes, where bound, with chromatin , Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRCC1 (Ser11) Conjugated
Short name FITC Conjugated, RCC1 (Ser11) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, RCC1 (Ser11) (Antibody to)
Alternative techniqueantibodies
Identity 1913
Gene RCC1
Long gene name regulator of chromosome condensation 1
Synonyms gene CHC1
Synonyms gene name chromosome condensation 1
Locus 1p35, 3
Discovery year 1986-01-01
GenBank acession X12654
Entrez gene record 1104
Pubmed identfication 7851910
RefSeq identity NM_001269
Havana BLAST/BLAT OTTHUMG00000003645

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