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Recombinant Human CD27 Ligand, TNFSF7, CD70 (C-Fc)

Recombinant Human CD27 Ligand, TNFSF7, CD70 (C-Fc) size: 1 mg 2283

Supplier NOVO
Price 2283
Size 1 mg
Reacts withHuman
Source proteins, Recombinants or rec
Description Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling
Molecular Weight43, 6 kD
UniProt numberP32970
State of the productFreeze-dried
Shipping conditionsAmbient temperature
Formulation2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0, pH 7
Storage recommendations -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRPVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Properties Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp
Grouprecombinants
Gene target CD70 (C-Fc), TNFSF7, CD27 Ligand
Short name CD70 (C-Fc), TNFSF7, Recombinant CD27 Ligand
Technique E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Species Humans, Human
Alternative name CD70 molecule (C-fragment c), TNFSF7, sapiens CD27 molecule Ligand, recombinant H
Alternative techniquerec
Alternative to gene target CD27 and IDBG-14014 and ENSG00000139193 and 939, CD27 and IDBG-640494 and ENSBTAG00000014725 and 512514, CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074, CD70 molecule, Cd27 and IDBG-189750 and ENSMUSG00000030336 and 21940, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, Extracellular, Extracellular, LPFS2 and T14 and TNFRSF7 and Tp55, S152 and S152, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, this GO :0002020 and protease binding and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0005102: receptor binding and also this GO :0005125: cytokine activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008588 and release of cytoplasmic sequestered NF-kappaB and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070233 and negative regulation of T cell apoptotic process and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0005102: receptor binding, this GO :0005125: cytokine activity, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, CD27 molecule
Identity 11937
Gene CD70
Long gene name CD70 molecule
Synonyms gene CD27LG TNFSF7
Synonyms gene name member 7 , tumor necrosis factor (ligand) superfamily
Synonyms CD27L
Locus 19p13, 3
Discovery year 1993-11-08
GenBank acession L08096
Entrez gene record 970
Pubmed identfication 8387892 8120384
Classification Tumor necrosis factor superfamily CD molecules
Havana BLAST/BLAT OTTHUMG00000181834

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