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Recombinant Human GITR Ligand, TNFSF18 (C-6His)

Recombinant Human GITR Ligand, TNFSF18 (C-6His) size: 1 mg 2283

Supplier NOVO
Price 2283
Size 1 mg
Reacts withHuman
Source proteins, Recombinants or rec
Description Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling
Molecular Weight15, 3 kD
UniProt numberQ9UNG2
State of the productFreeze-dried
Shipping conditionsAmbient temperature
Formulation2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0, pH 7
Storage recommendations -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidETAKEPCMAKFGPLPSKWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFISVDHHHHHH
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Properties Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp
Grouprecombinants
Gene target TNFSF18 (C-6His), GITR Ligand
Short name TNFSF18 (C-6His), Recombinant GITR Ligand
Technique E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Species Humans, Human
Alternative name member 18 (C-6His), sapiens GITR Ligand, tumor necrosis factor (ligand) superfamily, recombinant H
Alternative techniquerec
Alternative to gene target AITRL and GITRL and hGITRL and TL6, Extracellular, LOC768081 and IDBG-632315 and ENSBTAG00000047412 and 768081, TNFSF18 and IDBG-104861 and ENSG00000120337 and 8995, Tnfsf18 and IDBG-201543 and ENSMUSG00000066755 and 240873, member 18, this GO :0002309 and T cell proliferation involved in immune response and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032813 and tumor necrosis factor receptor superfamily binding and molecular function this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042129 and regulation of T cell proliferation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005125: cytokine activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005515: protein binding and also this GO :0032813: tumor necrosis factor receptor superfamily binding, this GO :0005125: cytokine activity, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005515: protein binding, this GO :0032813: tumor necrosis factor receptor superfamily binding, tumor necrosis factor receptor superfamily binding, tumor necrosis factor (ligand) superfamily
Identity 11932
Gene TNFSF18
Long gene name tumor necrosis factor superfamily member 18
Synonyms gene name member 18 , tumor necrosis factor (ligand) superfamily
Synonyms AITRL TL6 hGITRL
Locus 1q25, 1
Discovery year 1999-01-15
GenBank acession AF117713
Entrez gene record 8995
Pubmed identfication 10037686 10074428
RefSeq identity NM_005092
Classification Tumor necrosis factor superfamily
Havana BLAST/BLAT OTTHUMG00000034835

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