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Recombinant Human Neuroligin-1, NLGN1 (C-6His)
Recombinant Human Neuroligin-1, NLGN1 (C-6His) size: 500 µg 1613
Supplier
NOVO
Price
1613
Size
500 µg
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| Reacts with | Human |
| Source | proteins, Recombinants or rec |
| Description | Recombinant Human Neuroligin 1 is produced by our Mammalian expression system and the target gene encoding Gln46-Leu676 is expressed with a 6His tag at the C-terminus |
| Molecular Weight | 5 kD, 71 |
| UniProt number | Q8N2Q7 |
| State of the product | Freeze-dried |
| Shipping conditions | Ambient temperature |
| Formulation | 150 mM sodium chloride, pH 7, 2, 2 um filtered solution of 20 mM PB, Lyophilized from a 0 |
| Storage recommendations | -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution | Avoid mixing using vortex or pipettes, Dissolve the protein in ddH2O, In order to retain the quality and the affinity of the product unchanged, It is not recommended to dilute the product to less than 100 &mu, avoid cycles of freezing and thawing, please, The vials should be centrifuged before it is opened, g/ml |
| Purity | and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid | QKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQQPSPFSVDQRDYSTELVDHHHHHH |
| Levels of endotoxin | 11 IEU/ug, LAL test shows less than than 0 |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group | recombinants |
| Gene target | NLGN1 (C-6His), Neuroligin-1 |
| Short name | NLGN1 (C-6His), Recombinant Neuroligin-1 |
| Technique | E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species | Humans, Human |
| Alternative name | neuroligin 1 (C-6His), sapiens Neuroligin-1, recombinant H |
| Alternative technique | rec |
| Alternative to gene target | Cell surfaces, GABAergic and biological process this GO :0032433 and filopodium tip and cellular component this GO :0035418 and protein localization to synapse and biological process this GO :0042043 and neurexin family protein binding and molecular function this GO :0045184 and establishment of protein localization and biological process this GO :0045202 and synapse and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045664 and regulation of neuron differentiation and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048789 and cytoskeletal matrix organization at active zone and biological process this GO :0050804 and regulation of synaptic transmission and biological process this GO :0050808 and synapse organization and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051260 and protein homooli this GO merization and biological process this GO :0051290 and protein heterotetramerization and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0051965 and positive regulation of synapse assembly and biological process this GO :0051968 and positive regulation of synaptic transmission, NL1, NLGN1 and IDBG-636117 and ENSBTAG00000031891 and 530042, NLGN1 and IDBG-65853 and ENSG00000169760 and 22871, Nlgn1 and IDBG-133960 and ENSMUSG00000063887 and 192167, cell adhesion molecule binding, glutamatergic and biological process this GO :0060999 and positive regulation of dendritic spine development and biological process this GO :0072553 and terminal button organization and biological process this GO :0097091 and synaptic vesicle clustering and biological process this GO :0097104 and postsynaptic membrane assembly and biological process this GO :0097105 and presynaptic membrane assembly and biological process this GO :0097113 and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering and biological process this GO :0097114 and N-methyl-D-aspartate receptor clustering and biological process this GO :0097115 and neurexin clustering and biological process this GO :0097119 and postsynaptic density protein 95 clustering and biological process this GO :0097120 and receptor localization to synapse and biological process this GO :0097481 and neuronal postsynaptic density and cellular component this GO :1900029 and positive regulation of ruffle assembly and biological process this GO :1900244 and positive regulation of synaptic vesicle endocytosis and biological process this GO :1902533 and positive regulation of intracellular signal transduction and biological process this GO :2000302 and positive regulation of synaptic vesicle exocytosis and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process this GO :2000311 and regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity and biological process this GO :2000463 and positive regulation of excitatory postsynaptic membrane potential and biological process, this GO :0002087 and regulation of respiratory gaseous exchange by neurological system process and biological process this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006605 and protein targeting and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007158 and neuron cell-cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0008152 and metabolic process and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016080 and synaptic vesicle targeting and biological process this GO :0016339 and calcium-dependent cell-cell adhesion and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0017146 and N-methyl-D-aspartate selective glutamate receptor complex and cellular component this GO :0023041 and neuronal signal transduction and biological process this GO :0030054 and cell junction and cellular component this GO :0030165 and PDZ domain binding and molecular function this GO :0030425 and dendrite and cellular component this GO :0032230 and positive regulation of synaptic transmission, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0016787: hydrolase activity and also this GO :0030165: PDZ domain binding and also this GO :0042043: neurexin family protein binding and also this GO :0046983: protein dimerization activity and also this GO :0050839: cell adhesion molecule binding, this GO :0005515: protein binding, this GO :0016787: hydrolase activity, this GO :0030165: PDZ domain binding, this GO :0042043: neurexin family protein binding, this GO :0046983: protein dimerization activity, this GO :0050839: cell adhesion molecule binding, neuroligin 1 |
| Identity | 14291 |
| Gene | NLGN1 |
| Long gene name | neuroligin 1 |
| Synonyms | KIAA1070 |
| Locus | 3q26, 31 |
| Discovery year | 2001-01-02 |
| GenBank acession | AB028993 |
| Entrez gene record | 22871 |
| Pubmed identfication | 10767552 10819331 |
| RefSeq identity | NM_014932 |
| Havana BLAST/BLAT | OTTHUMG00000157005 |