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Recombinant Human Vitamin K-Dependent Protein C, PROC (C-6His)

Recombinant Human Vitamin K-Dependent Protein C, PROC (C-6His) size: 1 mg 2283

Supplier NOVO
Price 2283
Size 1 mg
Reacts withHuman
Source proteins, Recombinants or rec
DescriptionRecombinant Human Protein C is produced by our Mammalian expression system and the target gene encoding Thr19-Pro461 is expressed with a 6His tag at the C-terminus
Molecular Weight1 kD, 51
UniProt numberP04070
State of the productLiquid
Shipping conditionsDry ice/ice packs
Formulation10%Glycerol, 150 mM sodium chloride, 2 um filtered solution of 20 mM TrisHCl, 5, Supplied as a 0, pH7
Storage recommendations -20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAPLEHHHHHH
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Properties Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp
Grouprecombinants
Gene target PROC (C-6His), Vitamin K-Dependent Protein C
Short name PROC (C-6His), Recombinant Vitamin K-Dependent Protein C
Technique E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Species Humans, Human
Alternative name protein C (inactivator on coagulation factors Va and VIIIa) (C-6His), sapiens Vitamin K-Dependent Protein C, recombinant H
Alternative techniquerec
Alternative to gene target APC and PC and PROC1 and THPH3 and THPH4, Extracellular, PROC and IDBG-639221 and ENSBTAG00000003950 and 281428, PROC and IDBG-69078 and ENSG00000115718 and 5624, Proc and IDBG-133467 and ENSMUSG00000024386 and 19123, peptidase activity, this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007596 and blood coagulation and biological process this GO :0008233 and peptidase activity and molecular function this GO :0017187 and peptidyl-glutamic acid carboxylation and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0050900 and leukocyte migration and biological process, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004252: serine-type endopeptidase activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008233: peptidase activity, this GO :0004252: serine-type endopeptidase activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008233: peptidase activity, protein C (inactivator of coagulation factors Va and VIIIa)
Identity 9451
Gene PROC
Long gene name inactivator of coagulation factors Va and VIIIa , protein C
Synonyms gene name protein C (inactivator of coagulation factors Va and VIIIa)
Synonyms name prepro-protein C
Locus 2q14, 3
Discovery year 2001-06-22
GenBank acession X02750
Entrez gene record 5624
Pubmed identfication 2991887 2437584
RefSeq identity NM_000312
Classification Endogenous ligands Gla domain containing
Havana BLAST/BLAT OTTHUMG00000131528
Locus Specific Databases 3d Protein C Mutations Database LRG_599

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