Name : Recombinant Human Vitamin K-Dependent Protein C, PROC (C-6His)
Supplier : NOVO
Price :2283
SKU : GEN9915579691
| Reacts with | Human |
| Source | proteins, Recombinants or rec |
| Description | Recombinant Human Protein C is produced by our Mammalian expression system and the target gene encoding Thr19-Pro461 is expressed with a 6His tag at the C-terminus |
| Molecular Weight | 1 kD, 51 |
| UniProt number | P04070 |
| State of the product | Liquid |
| Shipping conditions | Dry ice/ice packs |
| Formulation | 10%Glycerol, 150 mM sodium chloride, 2 um filtered solution of 20 mM TrisHCl, 5, Supplied as a 0, pH7 |
| Storage recommendations | -20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution | Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity | and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid | TPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAPLEHHHHHH |
| Levels of endotoxin | 11 IEU/ug, LAL test shows less than than 0 |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group | recombinants |
| Gene target | PROC (C-6His), Vitamin K-Dependent Protein C |
| Short name | PROC (C-6His), Recombinant Vitamin K-Dependent Protein C |
| Technique | E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species | Humans, Human |
| Alternative name | protein C (inactivator on coagulation factors Va and VIIIa) (C-6His), sapiens Vitamin K-Dependent Protein C, recombinant H |
| Alternative technique | rec |
| Alternative to gene target | APC and PC and PROC1 and THPH3 and THPH4, Extracellular, PROC and IDBG-639221 and ENSBTAG00000003950 and 281428, PROC and IDBG-69078 and ENSG00000115718 and 5624, Proc and IDBG-133467 and ENSMUSG00000024386 and 19123, peptidase activity, this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007596 and blood coagulation and biological process this GO :0008233 and peptidase activity and molecular function this GO :0017187 and peptidyl-glutamic acid carboxylation and biological process this GO :0030195 and negative regulation of blood coagulation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0050900 and leukocyte migration and biological process, this GO :0003824: catalytic activity, this GO :0003824: catalytic activity and also this GO :0004252: serine-type endopeptidase activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0008233: peptidase activity, this GO :0004252: serine-type endopeptidase activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0008233: peptidase activity, protein C (inactivator of coagulation factors Va and VIIIa) |
| Identity | 9451 |
| Gene | PROC |
| Long gene name | inactivator of coagulation factors Va and VIIIa , protein C |
| Synonyms gene name | protein C (inactivator of coagulation factors Va and VIIIa) |
| Synonyms name | prepro-protein C |
| Locus | 2q14, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | X02750 |
| Entrez gene record | 5624 |
| Pubmed identfication | 2991887 2437584 |
| RefSeq identity | NM_000312 |
| Classification | Endogenous ligands Gla domain containing |
| Havana BLAST/BLAT | OTTHUMG00000131528 |
| Locus Specific Databases | 3d Protein C Mutations Database LRG_599 |