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Recombinant Mouse α-Synuclein, SNCA

Recombinant Mouse α-Synuclein, SNCA size: 500 µg 659

Supplier NOVO
Price 659
Size 500 µg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Reacts withMouse
Source proteins, Recombinants or rec
DescriptionRecombinant Mouse alpha-Synuclein is produced by our E, coli expression system and the target gene encoding Met1-Ala140 is expressed
Molecular Weight14, 5 kD
UniProt numberO55042
State of the productFreeze-dried
Shipping conditionsAmbient temperature
Formulation2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0, pH7
Storage recommendations -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidMDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGNIAAATGFVKKDQMGKGEEGYPQEGILEDMPVDPGSEAYEMPSEEGYQDYEPEA
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
Grouprecombinants
Gene target SNCA, &alpha, -Synuclein
Short name SNCA, -Synuclein, Recombinant Mouse &alpha
Technique E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
SpeciesMouses
Alternative name alpha (non A4 component on amyloid precursor), synuclein, -Synuclein, recombinant Mouse &alpha
Alternative techniquerec
Alternative to gene target NACP and PARK1 and PARK4 and PD1, SNCA and IDBG-30077 and ENSG00000145335 and 6622, SNCA and IDBG-641103 and ENSBTAG00000024957 and 282857, Snca and IDBG-152558 and ENSMUSG00000025889 and 20617, alpha (non A4 component of amyloid precursor), dopaminergic and biological process this GO :0005507 and copper ion binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005634 and nucleus and cellular component this GO :0005640 and nuclear outer membrane and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005764 and lysosome and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005840 and ribosome and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006631 and fatty acid metabolic process and biological process this GO :0006638 and neutral lipid metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007006 and mitochondrial membrane organization and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007568 and aging and biological process this GO :0008017 and microtubule binding and molecular function this GO :0008021 and synaptic vesicle and cellular component this GO :0008198 and ferrous iron binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0008344 and adult locomotory behavior and biological process this GO :0010040 and response to iron(II) ion and biological process this GO :0010517 and regulation of phospholipase activity and biological process this GO :0010642 and negative regulation of platelet-derived growth factor receptor signaling pathway and biological process this GO :0014048 and regulation of glutamate secretion and biological process this GO :0014059 and regulation of dopamine secretion and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016234 and inclusion body and cellular component this GO :0016491 and oxidoreductase activity and molecular function this GO :0019894 and kinesin binding and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030544 and Hsp70 protein binding and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0031115 and negative regulation of microtubule polymerization and biological process this GO :0031623 and receptor internalization and biological process this GO :0031648 and protein destabilization and biological process this GO :0032026 and response to magnesium ion and biological process this GO :0032410 and negative regulation of transporter activity and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032769 and negative regulation of monooxygenase activity and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034341 and response to interferon-gamma and biological process this GO :0034599 and cellular response to oxidative stress and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0040012 and regulation of locomotion and biological process this GO :0042220 and response to cocaine and biological process this GO :0042393 and histone binding and molecular function this GO :0042416 and dopamine biosynthetic process and biological process this GO :0042417 and dopamine metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042775 and mitochondrial ATP synthesis coupled electron transport and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043014 and alpha-tubulin binding and molecular function this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043030 and regulation of macrophage activation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043195 and terminal bouton and cellular component this GO :0043205 and fibril and cellular component this GO :0043206 and extracellular fibril organization and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043274 and phospholipase binding and molecular function this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043679 and axon terminus and cellular component this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0045087 and innate immune response and biological process this GO :0045202 and synapse and cellular component this GO :0045502 and dynein binding and molecular function this GO :0045807 and positive regulation of endocytosis and biological process this GO :0045920 and negative regulation of exocytosis and biological process this GO :0045963 and negative regulation of dopamine metabolic process and biological process this GO :0046928 and regulation of neurotransmitter secretion and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0048148 and behavioral response to cocaine and biological process this GO :0048156 and tau protein binding and molecular function this GO :0048168 and regulation of neuronal synaptic plasticity and biological process this GO :0048169 and regulation of long-term neuronal synaptic plasticity and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048487 and beta-tubulin binding and molecular function this GO :0048488 and synaptic vesicle endocytosis and biological process this GO :0048489 and synaptic vesicle transport and biological process this GO :0050544 and arachidonic acid binding and molecular function this GO :0050806 and positive regulation of synaptic transmission and biological process this GO :0050808 and synapse organization and biological process this GO :0050812 and regulation of acyl-CoA biosynthetic process and biological process this GO :0051219 and phosphoprotein binding and molecular function this GO :0051281 and positive regulation of release of sequestered calcium ion into cytosol and biological process this GO :0051583 and dopamine uptake involved in synaptic transmission and biological process this GO :0051585 and negative regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0051612 and negative regulation of serotonin uptake and biological process this GO :0051622 and negative regulation of norepinephrine uptake and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060079 and regulation of excitatory postsynaptic membrane potential and biological process this GO :0060291 and long-term synaptic potentiation and biological process this GO :0060732 and positive regulation of inositol phosphate biosynthetic process and biological process this GO :0061024 and membrane organization and biological process this GO :0070495 and negative regulation of thrombin receptor signaling pathway and biological process this GO :0070555 and response to interleukin-1 and biological process this GO :0071280 and cellular response to copper ion and biological process this GO :0071872 and cellular response to epinephrine stimulus and biological process this GO :0071902 and positive regulation of protein serine/threonine kinase activity and biological process this GO :1901214 and regulation of neuron death and biological process, nuclei, phosphoprotein binding, this GO :0000287 and magnesium ion binding and molecular function this GO :0001774 and microglial cell activation and biological process this GO :0001921 and positive regulation of receptor recycling and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001956 and positive regulation of neurotransmitter secretion and biological process this GO :0001963 and synaptic transmission, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0005507: copper ion binding and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0005543: phospholipid binding and also this GO :0008017: microtubule binding and also this GO :0008198: ferrous iron binding and also this GO :0008270: zinc ion binding and also this GO :0016491: oxidoreductase activity and also this GO :0019894: kinesin binding and also this GO :0019899: enzyme binding and also this GO :0019904: protein domain specific binding and also this GO :0030544: Hsp70 protein binding and also this GO :0042393: histone binding and also this GO :0042802: identical protein binding and also this GO :0043014: alpha-tubulin binding and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process and also this GO :0043274: phospholipase binding and also this GO :0045502: dynein binding and also this GO :0047485: protein N-terminus binding and also this GO :0048156: tau protein binding and also this GO :0048487: beta-tubulin binding and also this GO :0050544: arachidonic acid binding and also this GO :0051219: phosphoprotein binding, this GO :0005507: copper ion binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0005543: phospholipid binding, this GO :0008017: microtubule binding, this GO :0008198: ferrous iron binding, this GO :0008270: zinc ion binding, this GO :0016491: oxidoreductase activity, this GO :0019894: kinesin binding, this GO :0019899: enzyme binding, this GO :0019904: protein domain specific binding, this GO :0030544: Hsp70 protein binding, this GO :0042393: histone binding, this GO :0042802: identical protein binding, this GO :0043014: alpha-tubulin binding, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0043274: phospholipase binding, this GO :0045502: dynein binding, this GO :0047485: protein N-terminus binding, this GO :0048156: tau protein binding, this GO :0048487: beta-tubulin binding, this GO :0050544: arachidonic acid binding, this GO :0051219: phosphoprotein binding, synuclein
Identity 11138
Gene SNCA
Long gene name synuclein alpha
Synonyms gene PARK1 PARK4
Synonyms gene name Lewy body) 4 synuclein, Parkinson disease (autosomal dominant, alpha (non A4 component of amyloid precursor)
Synonyms NACP PD1 alpha-synuclein
Synonyms name non A4 component of amyloid precursor
Locus 4q22, 1
Discovery year 1995-01-24
GenBank acession L08850
Entrez gene record 6622
Pubmed identfication 8248242 14593171
Classification Parkinson disease associated genes
Havana BLAST/BLAT OTTHUMG00000130948
Locus Specific Databases Parkinson', s disease Mutation Database

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