Name : Recombinant Mouse Thrombopoietin, THPO, TPO (C-6His)
Supplier : NOVO
Price :1613
SKU : GEN3405178496
| Reacts with | Mouse |
| Source | proteins, Recombinants or rec |
| Description | Recombinant Mouse Thrombopoietin is produced by our Mammalian expression system and the target gene encoding Ser22­, Thr356 is expressed with a 6His tag at the C-terminus |
| Molecular Weight | 36, 4 kD |
| UniProt number | P40226 |
| State of the product | Freeze-dried |
| Shipping conditions | Ambient temperature |
| Formulation | pH7, 2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0 |
| Storage recommendations | -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution | Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity | and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid | SPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQETHHHHHH |
| Levels of endotoxin | 11 IEU/ug, LAL test shows less than than 0 |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or  |
| Latin name | Mus musculus |
| Group | recombinants |
| Gene target | THPO, TPO (C-6His), Thrombopoietin |
| Short name | THPO, TPO (C-6His), Recombinant Mouse Thrombopoietin |
| Technique | E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species | Mouses, Mouse |
| Alternative name | TPO (C-6His), thrombopoietin, recombinant Mouse Thrombopoietin |
| Alternative technique | rec |
| Alternative to gene target | Extracellular, MGDF and MKCSF and ML and MPLLG and THCYT1 and TPO, THPO and IDBG-635050 and ENSBTAG00000000476 and 538672, THPO and IDBG-68171 and ENSG00000090534 and 7066, Thpo and IDBG-146337 and ENSMUSG00000022847 and 21832, growth factor activity, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030168 and platelet activation and biological process this GO :0038163 and thrombopoietin-mediated signaling pathway and biological process this GO :0045654 and positive regulation of megakaryocyte differentiation and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005179: hormone activity and also this GO :0008083: growth factor activity, this GO :0005179: hormone activity, this GO :0008083: growth factor activity, thrombopoietin |
| Identity | 11795 |
| Gene | THPO |
| Long gene name | thrombopoietin |
| Synonyms gene | MGDF |
| Synonyms | TPO MPLLG |
| Synonyms name | prepro-thrombopoietin megakaryocyte stimulating factor myeloproliferative leukemia virus oncogene ligand megakaryocyte growth and development factor MPL ligand megakaryocyte colony-stimulating factor c-mpl ligand thrombopoietin nirs variant 1 |
| Locus | 3q27, 1 |
| Discovery year | 1994-11-04 |
| Entrez gene record | 7066 |
| Pubmed identfication | 8202154 |
| RefSeq identity | NM_000460 |
| Classification | Endogenous ligands |
| Havana BLAST/BLAT | OTTHUMG00000156745 |