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Recombinant Mouse Thrombopoietin, THPO, TPO (C-6His)

Recombinant Mouse Thrombopoietin, THPO, TPO (C-6His) size: 500 µg 1613

Supplier NOVO
Price 1613
Size 500 µg
Reacts withMouse
Source proteins, Recombinants or rec
DescriptionRecombinant Mouse Thrombopoietin is produced by our Mammalian expression system and the target gene encoding Ser22­, Thr356 is expressed with a 6His tag at the C-terminus
Molecular Weight36, 4 kD
UniProt numberP40226
State of the productFreeze-dried
Shipping conditionsAmbient temperature
Formulation pH7, 2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0
Storage recommendations -20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at <
Reconstitution Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml
Purity and determined by Polyacrylamide gel electrophoresis, Greater than 95%
Sequence of the amino acidSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDGHTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQETHHHHHH
Levels of endotoxin11 IEU/ug, LAL test shows less than than 0
Test A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or 
Latin nameMus musculus
Grouprecombinants
Gene target THPO, TPO (C-6His), Thrombopoietin
Short name THPO, TPO (C-6His), Recombinant Mouse Thrombopoietin
Technique E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli
Species Mouses, Mouse
Alternative name TPO (C-6His), thrombopoietin, recombinant Mouse Thrombopoietin
Alternative techniquerec
Alternative to gene target Extracellular, MGDF and MKCSF and ML and MPLLG and THCYT1 and TPO, THPO and IDBG-635050 and ENSBTAG00000000476 and 538672, THPO and IDBG-68171 and ENSG00000090534 and 7066, Thpo and IDBG-146337 and ENSMUSG00000022847 and 21832, growth factor activity, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005179 and hormone activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030168 and platelet activation and biological process this GO :0038163 and thrombopoietin-mediated signaling pathway and biological process this GO :0045654 and positive regulation of megakaryocyte differentiation and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005179: hormone activity and also this GO :0008083: growth factor activity, this GO :0005179: hormone activity, this GO :0008083: growth factor activity, thrombopoietin
Identity 11795
Gene THPO
Long gene name thrombopoietin
Synonyms gene MGDF
Synonyms TPO MPLLG
Synonyms name prepro-thrombopoietin megakaryocyte stimulating factor myeloproliferative leukemia virus oncogene ligand megakaryocyte growth and development factor MPL ligand megakaryocyte colony-stimulating factor c-mpl ligand thrombopoietin nirs variant 1
Locus 3q27, 1
Discovery year 1994-11-04
Entrez gene record 7066
Pubmed identfication 8202154
RefSeq identity NM_000460
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000156745

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