| Type | Yeast recombinant proteins with good glycosilation in smaal amounts for use as standard in ELISA kits |
| Description | Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Source | proteins, Recombinants or rec |
| Group | recombinants |
| Gene target | Swine CD40 Ligand (CD40LG) |
| Short name | Recombinant Swine CD40 Ligand (CD40LG) |
| Technique | E, Immunochemistry kits advises they will be reconstituted in a buffer soluion or culture medium for cell culture, coli recombinant proteins are , supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Alternative name | tumor necrosis factor receptor superfamily member 5 Ligand (CD40 molecule, tumor necrosis factor receptor superfamily member 5 ligand), recombinant swine CD40 molecule |
| Alternative technique | rec |
| Alternative to gene target | BT, Bp50 and CDW40 and p50 and TNFRSF5, CD154 and CD40L and gp39 and hCD40L and HIGM1 and IGM and IMD3 and T-BAM and TNFSF5 and TRAP, CD40 and IDBG-78904 and ENSG00000101017 and 958, CD40 ligand, CD40LG and IDBG-631246 and ENSBTAG00000017843 and 282387, CD40LG and IDBG-87653 and ENSG00000102245 and 959, Cd40 and IDBG-212533 and ENSMUSG00000017652 and 21939, Cd40lg and IDBG-147440 and ENSMUSG00000031132 and 21947, Extracellular, Extracellular, TNF receptor superfamily member 5, protein binding, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002768 and immune response-regulating cell surface receptor signaling pathway and biological process this GO :0003823 and antigen binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006954 and inflammatory response and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0035631 and CD40 receptor complex and cellular component this GO :0042100 and B cell proliferation and biological process this GO :0042113 and B cell activation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0090037 and positive regulation of protein kinase C signaling and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003823: antigen binding, this GO :0003823: antigen binding and also this GO :0004871: signal transducer activity and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0019899: enzyme binding and also this GO :0031625: ubiquitin protein ligase binding, this GO :0004871: signal transducer activity, this GO :0004872: receptor activity, this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005174 and CD40 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0042100 and B cell proliferation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045190 and isotype switching and biological process this GO :0048305 and immunoglobulin secretion and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051023 and regulation of immunoglobulin secretion and biological process this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005164: tumor necrosis factor receptor binding and also this GO :0005174: CD40 receptor binding and also this GO :0005515: protein binding, this GO :0005164: tumor necrosis factor receptor binding, this GO :0005174: CD40 receptor binding, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0019899: enzyme binding, this GO :0031625: ubiquitin protein ligase binding, ubiquitin protein ligase binding, 42498 and IDBG-643036 and ENSBTAG00000020736 and 286849, CD40 molecule |
| Identity | 11935 |
| Gene | CD40LG |
| Long gene name | CD40 ligand |
| Synonyms gene | HIGM1 IMD3 TNFSF5 |
| Synonyms gene name | member 5 (hyper-IgM syndrome) , tumor necrosis factor (ligand) superfamily |
| Synonyms | CD40L TRAP gp39 hCD40L CD154 |
| Synonyms name | CD40 antigen ligand tumor necrosis factor (ligand) superfamily member 5 T-B cell-activating molecule TNF-related activation protein hyper-IgM syndrome |
| Locus | Xq26, 3 |
| Discovery year | 1989-06-30 |
| GenBank acession | X67878 |
| Entrez gene record | 959 |
| Pubmed identfication | 1427881 7678782 |
| RefSeq identity | NM_000074 |
| Classification | Endogenous ligands Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000022512 |
| Locus Specific Databases | CD40Lbase: Mutation registry for X-linked Hyper-IgM syndrome Mental Retardation database LRG_141 |
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