Filters

Repulsive Guidance Molecule B Antibody

Repulsive Guidance Molecule B Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRepulsive Guidance Molecule B Antibody
Also known asRepulsive Guidance Molecule B Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRGMB/Repulsive Guidance Molecule B
SpecificityThis is a highly specific antibody against RGMB/Repulsive Guidance Molecule B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule B
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH), Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness, RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, RGMa and RGMb, RGMc, The RGM proteins are attached to the membrane by a GPI-anchor, They are repulsive for a group of axons, Two members of this family, also known as Hemojuvelin, are expressed in the nervous system, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut, netrins and slits, no receptor mechanism for RGM activation has been defined, semaphorins, those from the temporal half of the retina, The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DRG11-responsive axonal guidance and outgrowth of neurite, RGM b, RGM domain family member B, RGMB_HUMAN, Repulsive Guidance Molecule B, Rgmb, Dragon
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are 
Gene targetRepulsive Guidance Molecule B
Short nameRepulsive Guidance Molecule B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRepulsive Guidance Molecule B (Antibody to)
Alternative techniqueantibodies
Identity 26896
Gene RGMB
Long gene name repulsive guidance molecule family member b
Synonyms gene name RGM domain family, member B
Synonyms FLJ90406 DRAGON
Locus 5q15
Discovery year 2004-02-04
GenBank acession AK074887
Entrez gene record 285704
Pubmed identfication 19324014
RefSeq identity NM_173670
Havana BLAST/BLAT OTTHUMG00000162745

Similar products

Subscribe to our Newsletter