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Repulsive Guidance Molecule B Antibody, Biotin Conjugated

Repulsive Guidance Molecule B Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Repulsive Guidance Molecule B Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRGMB/Repulsive Guidance Molecule B
SpecificityThis is a highly specific antibody against RGMB/Repulsive Guidance Molecule B
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule B
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH), Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness, RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, RGMa and RGMb, RGMc, The RGM proteins are attached to the membrane by a GPI-anchor, They are repulsive for a group of axons, Two members of this family, also known as Hemojuvelin, are expressed in the nervous system, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut, netrins and slits, no receptor mechanism for RGM activation has been defined, semaphorins, those from the temporal half of the retina, The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DRG11-responsive axonal guidance and outgrowth of neurite, RGM b, RGM domain family member B, RGMB_HUMAN, Repulsive Guidance Molecule B, Rgmb, Dragon
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Description present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are 
Gene targetRepulsive Guidance Molecule B Conjugated
Short name Conjugated, Repulsive Guidance Molecule B Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Repulsive Guidance Molecule B (Antibody to)
Alternative techniqueantibodies

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