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REST Antibody

REST Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenREST
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the REST antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis REST antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q13127
PurityAntigen affinity
Description Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, thereby acting as a chromatin modifier, which in turn recruit histone deacetylase to the promoters of REST-regulated genes, Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells
ImmunogenA portion of amino acids 542-570 from the human protein was used as the immunogen for this REST antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the REST antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetREST
Short nameREST Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameREST (Antibody to)
Alternative techniqueantibodies
Identity 9966
Gene REST
Long gene name RE1 silencing transcription factor
Synonyms gene name RE1-silencing transcription factor
Synonyms NRSF XBR
Synonyms name neuron-restrictive silencer factor
Locus 4q12
Discovery year 1996-04-12
GenBank acession U13879
Entrez gene record 5978
Pubmed identfication 7871435 7697725
RefSeq identity NM_005612
Havana BLAST/BLAT OTTHUMG00000128770

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