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Reticulon 4 Antibody

Reticulon 4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameReticulon 4 Primary Polyclonal Antibody
Also known asReticulon 4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenReticulon 4
Specificity Based on the location of the target sequence this antibody will recognize all isoforms(Nogo-A, Nogo-B, and Nogo-C), This is a highly specific antibody against Reticulon 4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1115-1160/1162
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from Mouse Reticulon 4
Gene ID number68585
Swiss ProtQ99P72
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, Involved in down-regulation of growth, It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex, May inhibit BACE1 activity and amyloid precursor protein processing, Reticulon 4 regulates neurite fasciculation, The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells, and as a facilitator of neurite branching, branching and extension in the developing nervous system, stabilization of wiring and restriction of plasticity in the adult CNS, Reticulons are associated with the endoplasmic reticulum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ASY, Foocen, Foocen-M, Foocen-S, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Nogo protein, Nogo-A, Nogo-B, Nogo-C, RTN 4A, RTN 4B, RTN 4C, RTN-x, RTN-xL, RTN-xS, RTN4-B2, Reticulon-5, Rtn-T, Rtn4, euroendocrine-specific protein C homolog, Reticulon-4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetReticulon 4
Short nameReticulon 4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameReticulon 4 (Antibody to)
Alternative techniqueantibodies
Identity 18601
Gene RTN4R
Long gene name reticulon 4 receptor
Synonyms NOGOR
Locus 22q11, 21
Discovery year 2002-04-30
GenBank acession AF283463
Entrez gene record 65078
Pubmed identfication 11201742
Havana BLAST/BLAT OTTHUMG00000150572

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