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Reticulon 4 Antibody, FITC Conjugated

Reticulon 4 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, Reticulon 4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenReticulon 4
Specificity Based on the location of the target sequence this antibody will recognize all isoforms(Nogo-A, Nogo-B, and Nogo-C), This is a highly specific antibody against Reticulon 4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1115-1160/1162
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from Mouse Reticulon 4
Gene ID number68585
Swiss ProtQ99P72
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, Involved in down-regulation of growth, It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex, May inhibit BACE1 activity and amyloid precursor protein processing, Reticulon 4 regulates neurite fasciculation, The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells, and as a facilitator of neurite branching, branching and extension in the developing nervous system, stabilization of wiring and restriction of plasticity in the adult CNS, Reticulons are associated with the endoplasmic reticulum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ASY, Foocen, Foocen-M, Foocen-S, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Nogo protein, Nogo-A, Nogo-B, Nogo-C, RTN 4A, RTN 4B, RTN 4C, RTN-x, RTN-xL, RTN-xS, RTN4-B2, Reticulon-5, Rtn-T, Rtn4, euroendocrine-specific protein C homolog, Reticulon-4
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetReticulon 4 Conjugated
Short name FITC Conjugated, Reticulon 4 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Reticulon 4 (Antibody to)
Alternative techniqueantibodies

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