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RhoA/C Antibody, Biotin Conjugated

RhoA/C Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, RhoA/C Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRhoA/C
SpecificityThis is a highly specific antibody against RhoA/C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range90-140/193
Subcellular location Helical, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human RhoA
Gene ID number387, 389
Swiss ProtP61586
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activated by ARHGEF2, Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly, In turn, Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis, It controls the localization of APC and CLASP2 to the cell membrane, May be an activator of PLCE1, Plays an essential role in cleavage furrow formation, Required for the apical junction formation of keratinocyte cell-cell adhesion, Serves as a target for the yopT cysteine peptidase from Yersinia pestis, Stimulates PKN2 kinase activity, The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex, and Yersinia pseudotuberculosis, membrane-bound APC allows the localization of the MACF1 to the cell membrane, vector of the plague, via the regulation of GSK3B activity, which causes gastrointestinal disorders, which is required for microtubule capture and stabilization, which promotes the exchange of GDP for GTP, Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms ARH12, ARH9, ARHC, RHO12, RHOA, RHOH12, Rho cDNA clone 12, Rho cDNA clone 9, Rho-related GTP-binding protein RhoC, Transforming protein RhoA, h12, ARHA
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRhoA/C Conjugated
Short name Conjugated, RhoA/C Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ras homolog family member A/C (Antibody to)
Alternative techniqueantibodies

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