Name : RIAM Antibody
Supplier : NJS POLY
Price :389
SKU : GEN7088130865
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | RIAM |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ICC, IHC-F, IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes | Titration of the RIAM antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This RIAM antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q7Z5R6 |
| Purity | Antigen affinity |
| Description | By genomic sequence analysis, Inagaki et al, Lafuente et al, Lafuente et al, The proline-rich regions of RIAM suppressed AP1 transactivation, Using promoter-reporter gene assays, also called RARP1 and APBB1-Interacting Protein, as well as with RAP1-GTP, but not CRE sites, in all cell lines examined, is a protein that in humans is encoded by the APBB1IP gene, molecules that regulate actin dynamics, (2003) found that RIAM suppressed transcription from AP1 and SRE sites, (2004) found that the protein interacted with profilin and VASP, (2004) mapped the gene to chromosome 10p12, 1, RIAM (Rap1-interacting adaptor molecule) |
| Immunogen | An amino acid sequence from the C-terminus of human Rap1-interacting adaptor molecule (EQDFMSDLMKALQKKRGNVS) was used as the immunogen for this RIAM antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RIAM antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | RIAM |
| Short name | RIAM Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RIAM (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17379 |
| Gene | APBB1IP |
| Long gene name | amyloid beta precursor protein binding family B member 1 interacting protein |
| Synonyms gene name | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| Synonyms | INAG1 RIAM |
| Synonyms name | Rap1-GTP-interacting adaptor molecule |
| Locus | 10p12, 1 |
| Discovery year | 2003-03-07 |
| GenBank acession | AB085852 |
| Entrez gene record | 54518 |
| Pubmed identfication | 9407065 |
| RefSeq identity | NM_019043 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000017841 |