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RIC8A Antibody, FITC Conjugated

RIC8A Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, RIC8A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRIC8A
SpecificityThis is a highly specific antibody against RIC8A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human RIC8A
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Arf, Functioning as a guanine nucleotide exchange factor, G?q and G?o, RIC-8A (resistance to inhibitors of cholinesterase 8 homolog A), RIC-8A binds to GDP-associated substrates and exchanges bound GDP for free GTP, RIC-8A is expressed as three isoforms due to alternative splicing events, RIC-8A plays a role in regulating mitotic movement and may be involved in receptor-mediated ERK activation, Rab, Rap and Ran subfamilies, Rho/Rac, Sar, The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form, This activation is catalyzed by guanine nucleotide exchange factors (GEFs), Via its ability to stimulate protein function, all of which control multiple aspects of cell function, also known as RIC8 or Synembryn-A, including G?i-1, including cytoskeletal rearrangement, is a 530 amino acid cytoplasmic protein that can activate several G-alpha proteins, nuclear signaling and cell growth, The Ras superfamily of GTPases can be subdivided into the Ras
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms synembryn synembryn-A
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRIC8A Conjugated
Short name FITC Conjugated, RIC8A Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, RIC8A (Antibody to)
Alternative techniqueantibodies
Identity 29550
Gene RIC8A
Long gene name RIC8 guanine nucleotide exchange factor A
Synonyms gene name elegans) , resistance to inhibitors of cholinesterase 8 homolog A (C
Locus 11p15, 5
Discovery year 2005-08-17
GenBank acession AK022870
Entrez gene record 60626
Pubmed identfication 10985349 11230166
RefSeq identity NM_021932
Havana BLAST/BLAT OTTHUMG00000119069

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