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Rictor (Thr1135) Antibody, Biotin Conjugated

Rictor (Thr1135) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Rictor (Thr1135) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRictor Thr1135
Specificity This phosphorylation site is homologous to that of Thr1135 in Mouse and Thr1120 in Rat, This is a highly specific antibody against Rictor Thr1135
ModificationPhosphorylation
Modification siteThr1135
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1100-1150/1732
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human Rictor around the phosphorylation site of Thr1135
Gene ID number253260
Swiss ProtQ6R327
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Plays an essential role in embryonic growth and development, but, in contrast to mTORC1, mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657', mTORC2 is activated by growth factors, mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, mTORC2 promotes the serum-induced formation of stress-fibers or F-actin, mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422', mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors, seems to be nutrient-insensitive, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation, which regulates cell growth and survival in response to hormonal signals, Subunit of mTORC2
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms AVO3, AVO3 homolog, KIAA1999, RICTOR, Rapamycin-insensitive companion of mTOR, hAVO3, PIA
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRictor (Thr1135) Conjugated
Short name Conjugated, Rictor (Thr1135) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Rictor (Thr1135) (Antibody to)
Alternative techniqueantibodies

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