Name : RIP140 Antibody / NRIP1
Supplier : NJS POLY
Price :406
SKU : GEN8669829334
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | RIP140 / NRIP1 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 1-0, 5ug/ml, Western blot: 0 |
| Notes | Optimal dilution of the RIP140 antibody should be determined by the researcher |
| Intented use | This RIP140 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P48552 |
| Purity | Antigen affinity |
| Description | A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, Also known as RIP140, It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors, RIP140 has an important role in regulating lipid and glucose metabolism, also known as receptor-interacting protein 140 (RIP140), and liver, and regulates gene expression in metabolic tissues including heart, including the estrogen receptor, including uncoupling protein 1 and carnitine palmitoyltransferase 1b, is a protein that in humans is encoded by the NRIP1 gene, skeletal muscle, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, Nuclear receptor-interacting protein 1 (NRIP1) |
| Immunogen | Amino acids EAHLQQYSREHALKTQNANQAASERLAAMARLQE of human RIP140/NRIP1 were used as the immunogen for the RIP140 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RIP140 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | RIP140 / NRIP1 |
| Short name | RIP140 Antibody / NRIP1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RIP140 (Antibody to) / NRIP1 |
| Alternative technique | antibodies |
| Identity | 8001 |
| Gene | NRIP1 |
| Long gene name | nuclear receptor interacting protein 1 |
| Synonyms | RIP140 |
| Synonyms name | receptor interacting protein 140 nuclear factor RIP140 |
| Locus | 21q11, 1 , 2-q21 |
| Discovery year | 1998-12-18 |
| GenBank acession | X84373 |
| Entrez gene record | 8204 |
| Pubmed identfication | 7641693 9521594 |
| RefSeq identity | NM_003489 |
| Havana BLAST/BLAT | OTTHUMG00000074323 |