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RIT1 Antibody, ALEXA FLUOR 488

RIT1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, RIT1 Polyclonal Antibody
Also known asAnti-RIT1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRIT1
SpecificityThis is a highly specific antibody against RIT1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RIT1
Gene ID Number6016
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Calmodulin is a primary mediator of Ca2+ signals in the nervous system, In addition, In conclusion, Ric, Rin and Rit (Ric-related gene expressed in many tissues), Rin binds calmodulin through a C-terminal binding motif, Rit and Ric are widely expressed, Rit and Rin define a novel subfamily of Ras-related proteins, Rit and Rin lack the recognition signal for C-terminal prenylation, Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin, share related G2 domains with Ric, two Ras-like human proteins, whereas expression of Rin is restricted to the neuron system, which are 71% and 66% identical to RIC respectively, which provides a mechanism for membrane association, which then serves as a second messenger to direct diverse cellular responses, Neuronal activity dramatically increases the concentration of cytosolic Ca2+, Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms RIBB ROC1 MGC125864 MGC125865
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RIT1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetRIT1
Short nameRIT1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, RIT1 (Antibody to)
Alternative techniqueantibodies
Identity 10023
Gene RIT1
Long gene name Ras like without CAAX 1
Synonyms gene RIT
Synonyms gene name Ric (Drosophila)-like, expressed in many tissues
Synonyms name Ric-like, expressed in many tissues GTP-binding protein Roc1
Locus 1q22
Discovery year 1996-08-28
GenBank acession AF084462
Entrez gene record 6016
Pubmed identfication 8824319 8918462
RefSeq identity NM_006912
Classification RAS type GTPase family
Havana BLAST/BLAT OTTHUMG00000014104

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