Name : RIT1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4566802797
| Long name | ALEXA FLUOR 594 Conjugated, RIT1 Polyclonal Antibody |
| Also known as | Anti-RIT1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RIT1 |
| Specificity | This is a highly specific antibody against RIT1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RIT1 |
| Gene ID Number | 6016 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Calmodulin is a primary mediator of Ca2+ signals in the nervous system, In addition, In conclusion, Ric, Rin and Rit (Ric-related gene expressed in many tissues), Rin binds calmodulin through a C-terminal binding motif, Rit and Ric are widely expressed, Rit and Rin define a novel subfamily of Ras-related proteins, Rit and Rin lack the recognition signal for C-terminal prenylation, Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin, share related G2 domains with Ric, two Ras-like human proteins, whereas expression of Rin is restricted to the neuron system, which are 71% and 66% identical to RIC respectively, which provides a mechanism for membrane association, which then serves as a second messenger to direct diverse cellular responses, Neuronal activity dramatically increases the concentration of cytosolic Ca2+, Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | RIBB ROC1 MGC125864 MGC125865 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | RIT1 |
| Short name | RIT1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, RIT1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10023 |
| Gene | RIT1 |
| Long gene name | Ras like without CAAX 1 |
| Synonyms gene | RIT |
| Synonyms gene name | Ric (Drosophila)-like, expressed in many tissues |
| Synonyms name | Ric-like, expressed in many tissues GTP-binding protein Roc1 |
| Locus | 1q22 |
| Discovery year | 1996-08-28 |
| GenBank acession | AF084462 |
| Entrez gene record | 6016 |
| Pubmed identfication | 8824319 8918462 |
| RefSeq identity | NM_006912 |
| Classification | RAS type GTPase family |
| Havana BLAST/BLAT | OTTHUMG00000014104 |