RIT1 Antibody, Biotin Conjugated

RIT1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, RIT1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	RIT1
Specificity	This is a highly specific antibody against RIT1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human RIT1
Gene ID number	6016
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Calmodulin is a primary mediator of Ca2+ signals in the nervous system, In addition, In conclusion, Ric, Rin and Rit (Ric-related gene expressed in many tissues), Rin binds calmodulin through a C-terminal binding motif, Rit and Ric are widely expressed, Rit and Rin define a novel subfamily of Ras-related proteins, Rit and Rin lack the recognition signal for C-terminal prenylation, Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin, share related G2 domains with Ric, two Ras-like human proteins, whereas expression of Rin is restricted to the neuron system, which are 71% and 66% identical to RIC respectively, which provides a mechanism for membrane association, which then serves as a second messenger to direct diverse cellular responses, Neuronal activity dramatically increases the concentration of cytosolic Ca2+, Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	RIBB ROC1 MGC125864 MGC125865
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	RIT1 Conjugated
Short name	Conjugated, RIT1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, RIT1 (Antibody to)
Alternative technique	antibodies
Identity	10023
Gene	RIT1
Long gene name	Ras like without CAAX 1
Synonyms gene	RIT
Synonyms gene name	Ric (Drosophila)-like, expressed in many tissues
Synonyms name	Ric-like, expressed in many tissues GTP-binding protein Roc1
Locus	1q22
Discovery year	1996-08-28
GenBank acession	AF084462
Entrez gene record	6016
Pubmed identfication	8824319 8918462
RefSeq identity	NM_006912
Classification	RAS type GTPase family
Havana BLAST/BLAT	OTTHUMG00000014104

RIT1 Antibody, Biotin Conjugated

RIT1 Antibody, Biotin Conjugated size: 0.1ml 333

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