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RIT1 Antibody, Cy5.5 Conjugated

RIT1 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5, 5 Conjugated, RIT1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRIT1
SpecificityThis is a highly specific antibody against RIT1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human RIT1
Gene ID number6016
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Calmodulin is a primary mediator of Ca2+ signals in the nervous system, In addition, In conclusion, Ric, Rin and Rit (Ric-related gene expressed in many tissues), Rin binds calmodulin through a C-terminal binding motif, Rit and Ric are widely expressed, Rit and Rin define a novel subfamily of Ras-related proteins, Rit and Rin lack the recognition signal for C-terminal prenylation, Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin, share related G2 domains with Ric, two Ras-like human proteins, whereas expression of Rin is restricted to the neuron system, which are 71% and 66% identical to RIC respectively, which provides a mechanism for membrane association, which then serves as a second messenger to direct diverse cellular responses, Neuronal activity dramatically increases the concentration of cytosolic Ca2+, Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms RIBB ROC1 MGC125864 MGC125865
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetRIT1 Conjugated
Short name Conjugated, RIT1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, RIT1 (Antibody to)
Alternative techniqueantibodies
Identity 10023
Gene RIT1
Long gene name Ras like without CAAX 1
Synonyms gene RIT
Synonyms gene name Ric (Drosophila)-like, expressed in many tissues
Synonyms name Ric-like, expressed in many tissues GTP-binding protein Roc1
Locus 1q22
Discovery year 1996-08-28
GenBank acession AF084462
Entrez gene record 6016
Pubmed identfication 8824319 8918462
RefSeq identity NM_006912
Classification RAS type GTPase family
Havana BLAST/BLAT OTTHUMG00000014104

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