Name : RNF12 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4708112221
| Long name | ALEXA FLUOR 594 Conjugated, RNF12 Polyclonal Antibody |
| Also known as | Anti-RNF12 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RNF12 |
| Specificity | This is a highly specific antibody against RNF12 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 550-600/624 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF12 |
| Gene ID Number | 51132 |
| Swiss Prot | Q9NVW2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex, By targeting ZFP42 for degradation, Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1, Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals, acts as an activator of random inactivation of X chromosome in the embryo, E3 ubiquitin-protein ligase |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | NY-REN-43 MGC15161 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | RNF12 |
| Short name | RNF12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, RNF12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13429 |
| Gene | RLIM |
| Long gene name | LIM domain interacting , ring finger protein |
| Synonyms gene | RNF12 |
| Synonyms gene name | ring finger protein 12 |
| Synonyms name | ring zinc finger protein NY-REN-43antigen LIM domain interacting ring finger protein E3 ubiquitin-protein ligase RLIM |
| Locus | Xq13, 2 |
| Discovery year | 2002-04-30 |
| GenBank acession | AF155109 |
| Entrez gene record | 51132 |
| Pubmed identfication | 10508479 |
| RefSeq identity | NM_016120 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000021859 |
| Locus Specific Databases | Mental Retardation database |