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RNF12 Antibody, Biotin Conjugated

RNF12 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, RNF12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF12
SpecificityThis is a highly specific antibody against RNF12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range550-600/624
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human RNF12
Gene ID number51132
Swiss ProtQ9NVW2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex, By targeting ZFP42 for degradation, Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1, Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals, acts as an activator of random inactivation of X chromosome in the embryo, E3 ubiquitin-protein ligase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms NY-REN-43 MGC15161
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF12 Conjugated
Short name Conjugated, RNF12 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, RNF12 (Antibody to)
Alternative techniqueantibodies
Identity 13429
Gene RLIM
Long gene name LIM domain interacting , ring finger protein
Synonyms gene RNF12
Synonyms gene name ring finger protein 12
Synonyms name ring zinc finger protein NY-REN-43antigen LIM domain interacting ring finger protein E3 ubiquitin-protein ligase RLIM
Locus Xq13, 2
Discovery year 2002-04-30
GenBank acession AF155109
Entrez gene record 51132
Pubmed identfication 10508479
RefSeq identity NM_016120
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000021859
Locus Specific Databases Mental Retardation database

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