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RNF126 Antibody, Biotin Conjugated

RNF126 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, RNF126 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF126
SpecificityThis is a highly specific antibody against RNF126
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range80-130/313
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human RNF126
Gene ID number55658
Swiss ProtQ9BV68
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background By ubiquitinating CDKN1A/p21 and targeting it for degradation, Depending on the associated E2 ligase, FLT3, MET and CXCR4, May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, May also play a role in the endosomal recycling of IGF2R, May monoubiquitinate AICDA (PubMed:23277564), May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174), Through their polyubiquitination, may also promote cell proliferation (PubMed:23026136), may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, the cation-independent mannose-6-phosphate receptor (PubMed:24275455), E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ20552
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF126 Conjugated
Short name Conjugated, RNF126 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, RNF126 (Antibody to)
Alternative techniqueantibodies
Identity 21151
Gene RNF126
Long gene name ring finger protein 126
Locus 19p13, 3
Discovery year 2003-05-21
GenBank acession BC025374
Entrez gene record 55658
RefSeq identity NM_017876
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000180592

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