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RNF126 Antibody, Cy5.5 Conjugated

RNF126 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5, 5 Conjugated, RNF126 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF126
SpecificityThis is a highly specific antibody against RNF126
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range80-130/313
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human RNF126
Gene ID number55658
Swiss ProtQ9BV68
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background By ubiquitinating CDKN1A/p21 and targeting it for degradation, Depending on the associated E2 ligase, FLT3, MET and CXCR4, May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, May also play a role in the endosomal recycling of IGF2R, May monoubiquitinate AICDA (PubMed:23277564), May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174), Through their polyubiquitination, may also promote cell proliferation (PubMed:23026136), may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, the cation-independent mannose-6-phosphate receptor (PubMed:24275455), E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms FLJ20552
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetRNF126 Conjugated
Short name Conjugated, RNF126 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, RNF126 (Antibody to)
Alternative techniqueantibodies
Identity 21151
Gene RNF126
Long gene name ring finger protein 126
Locus 19p13, 3
Discovery year 2003-05-21
GenBank acession BC025374
Entrez gene record 55658
RefSeq identity NM_017876
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000180592

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