Name : RNF126 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN8387451176
| Long name | Cy5, 5 Conjugated, RNF126 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RNF126 |
| Specificity | This is a highly specific antibody against RNF126 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 80-130/313 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human RNF126 |
| Gene ID number | 55658 |
| Swiss Prot | Q9BV68 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | By ubiquitinating CDKN1A/p21 and targeting it for degradation, Depending on the associated E2 ligase, FLT3, MET and CXCR4, May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, May also play a role in the endosomal recycling of IGF2R, May monoubiquitinate AICDA (PubMed:23277564), May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174), Through their polyubiquitination, may also promote cell proliferation (PubMed:23026136), may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, the cation-independent mannose-6-phosphate receptor (PubMed:24275455), E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | FLJ20552 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | RNF126 Conjugated |
| Short name | Conjugated, RNF126 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, RNF126 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 21151 |
| Gene | RNF126 |
| Long gene name | ring finger protein 126 |
| Locus | 19p13, 3 |
| Discovery year | 2003-05-21 |
| GenBank acession | BC025374 |
| Entrez gene record | 55658 |
| RefSeq identity | NM_017876 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000180592 |