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RNF135 Antibody

RNF135 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNF135 Primary Polyclonal Antibody
Also known asRNF135 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF135
SpecificityThis is a highly specific antibody against RNF135
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF135
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, Multiple isoforms of RNF135 exist due to alternative splicing events, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF135 (RING finger protein 135), RNF135 may play a role in transcriptional regulation and protein degradation events, Via its RING-type zinc finger, also known as L13, facial dysmorphism and increased weight and height, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MGC13061, RN135_HUMAN , ring finger protein 135, L13
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF135
Short nameRNF135 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namering finger protein 135 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, Cytoplasm, RNF135 and IDBG-39370 and ENSG00000181481 and 84282, Rnf135 and IDBG-204021 and ENSMUSG00000020707 and 71956, metal ion binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0043021 and ribonucleoprotein complex binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0043021: ribonucleoprotein complex binding and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0043021: ribonucleoprotein complex binding, this GO :0046872: metal ion binding, 65952 and IDBG-631087 and ENSBTAG00000017225 and 511125, ring finger protein 135
Identity 21158
Gene RNF135
Long gene name ring finger protein 135
Synonyms MGC13061
Synonyms name riplet
Locus 17q11, 2
Discovery year 2003-05-21
GenBank acession AJ496729
Entrez gene record 84282
Pubmed identfication 11468690 19017631
RefSeq identity NM_032322
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000132867
Locus Specific Databases LOVD - Leiden Open Variation Database

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