Name : RNF142 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5211539175
| Long name | FITC Conjugated, RNF142 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RNF142 |
| Specificity | This is a highly specific antibody against RNF142 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human SH3MD2/RNF142 |
| Gene ID number | 57630 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | MAP2K7 and JNKs (MAPK8 and MAPK9), SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane, The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, There are two named isoforms, This gene encodes a protein containing an N-terminus RING-finger, Via the RING-finger, Within a signaling complex, and a region implicated in binding of the Rho GTPase Rac, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis, facilitating the formation of a functional signaling module, four SH3 domains, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network, SH3MD2 acts as a scaffold protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | POSH RNF142 KIAA1494 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RNF142 Conjugated |
| Short name | FITC Conjugated, RNF142 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, RNF142 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17650 |
| Gene | SH3RF1 |
| Long gene name | SH3 domain containing ring finger 1 |
| Synonyms gene | SH3MD2 |
| Synonyms gene name | SH3 multiple domains 2 |
| Synonyms name | plenty of SH3 domains |
| Locus | 4q32, 3-q33 |
| Discovery year | 2003-12-01 |
| GenBank acession | BC033203 |
| Entrez gene record | 57630 |
| Pubmed identfication | 9482736 |
| RefSeq identity | NM_020870 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000161010 |