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RNF144B Antibody

RNF144B Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNF144B Primary Polyclonal Antibody
Also known asRNF144B PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF144B
SpecificityThis is a highly specific antibody against RNF144B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IBRDC2/RING finger protein 144B
Gene ID number255488
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen But, However, Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism, a pro-apoptotic protein, and highest levels detectable in heart, it is not an anti-apoptotic protein per se, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, ovary and testis, thereby promoting their degradation, ultimately leading to protection of cell death, with lowest levels in brain and thymus, E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, Tissue specificity: Broadly expressed
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E3 ubiquitin-protein ligase RNF144B, IBR domain containing 2, IBR domain containing protein 2, IBR domain-containing protein 2, IBRDC 2, IBRDC2, PIR2, R144B_HUMAN, RING finger protein 144B, RING finger protein 144B, RNF 144B, RNF144B, Ring finger 144B, p53 inducible RING finger protein, p53-inducible RING finger protein, p53RFP, E3 ubiquitin protein ligase RNF144B
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF144B
Short nameRNF144B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namering finger protein 144B (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, Plasma membranes, RNF144B and IDBG-64050 and ENSG00000137393 and 255488, Rnf144b and IDBG-149475 and ENSMUSG00000038068 and 218215, ligase activity, this GO :0000151 and ubiquitin ligase complex and cellular component this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016874 and ligase activity and molecular function this GO :0031966 and mitochondrial membrane and cellular component this GO :0042787 and protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, 66635 and IDBG-635837 and ENSBTAG00000009055 and 524166, ring finger protein 144B
Identity 21578
Gene RNF144B
Long gene name ring finger protein 144B
Synonyms gene IBRDC2
Synonyms gene name IBR domain containing 2
Synonyms bA528A10, 3 P53RFP
Locus 6p22, 3
Discovery year 2003-06-25
GenBank acession AK096832
Entrez gene record 255488
RefSeq identity XM_172581
Classification Ring finger proteins RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000014322

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