Name : RNF180 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3428764452
| Long name | Biotin Conjugated, RNF180 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RNF180 |
| Specificity | This is a highly specific antibody against RNF180 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human RNF180 |
| Gene ID number | 285671 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, Expressed as three alternatively spliced isoforms, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF180 (ring finger protein 180), RNF180 is an E3 ubiquitin ligase involved in the ubiquitin-proteasome pathway, RNF180 is encoded by a gene located on human chromosome 5, RNF180 is expressed in brain, RNF180 is well conserved among vertebrates, also known as Rines, is a 592 single-pass membrane protein that contains a single RING-type zinc finger, is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome, kidney, or of chromosome 5 altogether, testis and uterus and localizes to the endoplasmic reticulum, which contains 181 million base pairs and comprises nearly 6% of the human genome, while deletion of the q arm, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RNF180 Conjugated |
| Short name | Conjugated, RNF180 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, RNF180 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 27752 |
| Gene | RNF180 |
| Long gene name | ring finger protein 180 |
| Locus | 5q12, 3 |
| Discovery year | 2005-01-26 |
| GenBank acession | AK090756 |
| Entrez gene record | 285671 |
| RefSeq identity | NM_178532 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000162278 |