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RNF20 (1594CT552.128.36) Monoclonal Antibody

RNF20 (1594CT552.128.36) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name128, 36) Monoclonal Antibody, RNF20 (1594CT552
Also known as128, 36) Monoclonal Antibody, RNF20 (1594CT552
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF20
SpecificityThis is a highly specific antibody against RNF20
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number36, 128, 1594CT552
SourceThis RNF20 antibody is generated from a mouse immunized with a recombinant protein of human RNF20
Gene ID number56254
Swiss ProtQ5VTR2
Tested ApplicationsWB
Recommended dilutionsWB(1:2000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, It thereby plays a central role inb histone code and gene regulation, Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation, Recruited to the MDM2 promoter, Required for transcriptional activation of Hox genes, The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, and thereby acts as a transcriptional coactivator, probably by being recruited by p53/TP53, reports about the cooperation with UBE2E1/UBCH are contradictory, respectively), Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1)
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRE1-A, BRE1A, E3 ubiquitin-protein ligase BRE1A, RING finger protein 20, RNF20, hBRE1, BRE1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target128, 36) Monoclonal, RNF20 (1594CT552
Short name128, 36) Monoclonal Antibody, RNF20 (1594CT552
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name128, 36) monoclonal (Antibody to), RNF20 (1594CT552
Alternative techniqueantibodies
Identity 10062
Gene RNF20
Long gene name ring finger protein 20
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein 20 ring finger protein 20
Synonyms FLJ20382 FLJ11189 KAIA2779 BRE1A hBRE1 BRE1
Synonyms name BRE1 E3 ubiquitin ligase homolog (S, cerevisiae)
Locus 9q31, 1
Discovery year 2000-05-23
GenBank acession AF265230
Entrez gene record 56254
Pubmed identfication 16337599 12876294 18832071 19037095
RefSeq identity NM_019592
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000020385

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