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RNF31 Antibody

RNF31 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNF31 Primary Polyclonal Antibody
Also known asRNF31 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF31
SpecificityThis is a highly specific antibody against RNF31
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF31
Gene ID number55072
Swiss ProtQ96EP0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds polyubiquitin of different linkage types, LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways, LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex, Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation, Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis, E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E3 ubiquitin-protein ligase RNF31, HOIL-1-interacting protein, RING finger protein 31, RNF31, ZIBRA, Zinc in-between-RING-finger ubiquitin-associated domain protein, HOIP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF31
Short nameRNF31 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameE3 ubiquitin-protein ligase RNF31 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target IRF-9 and ISGF3 and ISGF3G and p48, RNF31 and IDBG-544948 and ENSG00000259529 and 10379, multiple, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0071797 and LUBAC complex and cellular component, this GO :0004842: ubiquitin-protein transferase activity, this GO :0004842: ubiquitin-protein transferase activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, zinc ion binding, E3 ubiquitin-protein ligase RNF31
Identity 16031
Gene RNF31
Long gene name ring finger protein 31
Synonyms ZIBRA FLJ10111 FLJ23501 HOIP Paul
Synonyms name HOIL-1-interacting protein
Locus 14q12
Discovery year 2003-09-29
GenBank acession AK000973
Entrez gene record 55072
Pubmed identfication 10422847
RefSeq identity NM_017999
Classification Zinc fingers RANBP2-type Ring finger proteins Linear ubiquitin chain assembly complex RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000028798

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