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RNF56 Antibody, ALEXA FLUOR 594

RNF56 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, RNF56 Polyclonal Antibody
Also known asAnti-RNF56 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF56
SpecificityThis is a highly specific antibody against RNF56
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range90-140/982
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF56/CBL-B
Gene ID Number868
Swiss ProtQ13191
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also acts by promoting PIK3R1/p85 ubiquitination, BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In B-cells, In activated T-cells, In naive T-cells, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, May be involved in EGFR ubiquitination and internalization, Negatively regulates TCR (T-cell receptor), Slightly promotes SRC ubiquitination, acts by ubiquitinating SYK and promoting its proteasomal degradation, and transfers it to substrates, generally promoting their degradation by the proteasome, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, which impairs its recruitment to the TCR and subsequent activation, E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms RNF56 Cbl-b
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetRNF56
Short nameRNF56 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, RNF56 (Antibody to)
Alternative techniqueantibodies
Identity 1542
Gene CBLB
Long gene name Cbl proto-oncogene B
Synonyms gene name Cas-Br-M (murine) ectropic retroviral transforming sequence b Cas-Br-M (murine) ecotropic retroviral transforming sequence b Cbl proto-oncogene B, E3 ubiquitin protein ligase
Locus 3q13, 11
Discovery year 1995-12-18
GenBank acession U26710
Entrez gene record 868
Pubmed identfication 7784085
RefSeq identity NM_170662
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000150654

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