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RNF56 Antibody, Biotin Conjugated

RNF56 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, RNF56 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF56
SpecificityThis is a highly specific antibody against RNF56
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range90-140/982
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human RNF56/CBL-B
Gene ID number868
Swiss ProtQ13191
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also acts by promoting PIK3R1/p85 ubiquitination, BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In B-cells, In activated T-cells, In naive T-cells, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, May be involved in EGFR ubiquitination and internalization, Negatively regulates TCR (T-cell receptor), Slightly promotes SRC ubiquitination, acts by ubiquitinating SYK and promoting its proteasomal degradation, and transfers it to substrates, generally promoting their degradation by the proteasome, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, which impairs its recruitment to the TCR and subsequent activation, E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms RNF56 Cbl-b
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF56 Conjugated
Short name Conjugated, RNF56 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, RNF56 (Antibody to)
Alternative techniqueantibodies
Identity 1542
Gene CBLB
Long gene name Cbl proto-oncogene B
Synonyms gene name Cas-Br-M (murine) ectropic retroviral transforming sequence b Cas-Br-M (murine) ecotropic retroviral transforming sequence b Cbl proto-oncogene B, E3 ubiquitin protein ligase
Locus 3q13, 11
Discovery year 1995-12-18
GenBank acession U26710
Entrez gene record 868
Pubmed identfication 7784085
RefSeq identity NM_170662
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000150654

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