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RNF75 Antibody, FITC Conjugated

RNF75 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, RNF75 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF75
SpecificityThis is a highly specific antibody against RNF75
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ROC1/RNF75
Gene ID number9978
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation, CUL2, CUL4 and CUL4 via its interaction with UBE2M, May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair, Probably also stimulates CDC34 autoubiquitination, Promotes the neddylation of CUL1, The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components, Through the RING-type zinc finger, including proteins involved in cell cycle progression, like CDC34, seems to recruit the E2 ubiquitination enzyme, signal transduction, to the complex and brings it into close proximity to the substrate, transcription and transcription-coupled nucleotide excision repair, E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ROC1 RNF75 BA554C12, 1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF75 Conjugated
Short name FITC Conjugated, RNF75 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, RNF75 (Antibody to)
Alternative techniqueantibodies
Identity 9928
Gene RBX1
Long gene name ring-box 1
Synonyms gene name E3 ubiquitin protein ligase , ring-box 1 ring-box 1
Synonyms name regulator of cullins 1
Locus 22q13, 2
Discovery year 1999-10-29
GenBank acession AF140598
Entrez gene record 9978
Pubmed identfication 10213691 10230407
RefSeq identity NM_014248
Classification Ring finger proteins SCF complex
Havana BLAST/BLAT OTTHUMG00000151298

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