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RNF8 Antibody, ALEXA FLUOR 488

RNF8 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, RNF8 Polyclonal Antibody
Also known asAnti-RNF8 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF8
SpecificityThis is a highly specific antibody against RNF8
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF8
Gene ID Number9025
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation, RNF8 also binds to Retinoid X receptor alpha (RXR?, RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase, RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains, The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, The ring finger protein (RNF) family includes any protein containing the signature RING finger motif, a member of the steroid hormone receptor superfamily, and they co-localize in the nucleus, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity, The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms KIAA0646
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the RNF8 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetRNF8
Short nameRNF8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, RNF8 (Antibody to)
Alternative techniqueantibodies
Identity 10071
Gene RNF8
Long gene name ring finger protein 8
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein (C3HC4 type) 8 ring finger protein 8 ring finger protein 8
Locus 6p21, 2
Discovery year 1999-09-29
GenBank acession AB012770
Entrez gene record 9025
Pubmed identfication 9734811 9852682
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000014620

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