RNF8 Antibody, Biotin Conjugated

RNF8 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, RNF8 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	RNF8
Specificity	This is a highly specific antibody against RNF8
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human RNF8
Gene ID number	9025
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation, RNF8 also binds to Retinoid X receptor alpha (RXR?, RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase, RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains, The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, The ring finger protein (RNF) family includes any protein containing the signature RING finger motif, a member of the steroid hormone receptor superfamily, and they co-localize in the nucleus, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity, The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	KIAA0646
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	RNF8 Conjugated
Short name	Conjugated, RNF8 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, RNF8 (Antibody to)
Alternative technique	antibodies
Identity	10071
Gene	RNF8
Long gene name	ring finger protein 8
Synonyms gene name	E3 ubiquitin protein ligase , ring finger protein (C3HC4 type) 8 ring finger protein 8 ring finger protein 8
Locus	6p21, 2
Discovery year	1999-09-29
GenBank acession	AB012770
Entrez gene record	9025
Pubmed identfication	9734811 9852682
Classification	Ring finger proteins
Havana BLAST/BLAT	OTTHUMG00000014620

RNF8 Antibody, Biotin Conjugated

RNF8 Antibody, Biotin Conjugated size: 0.1ml 333

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