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RNF8 Antibody, Cy3 Conjugated

RNF8 Antibody, Cy3 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy3 Conjugated, RNF8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRNF8
SpecificityThis is a highly specific antibody against RNF8
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human RNF8
Gene ID number9025
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation, RNF8 also binds to Retinoid X receptor alpha (RXR?, RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase, RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains, The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, The ring finger protein (RNF) family includes any protein containing the signature RING finger motif, a member of the steroid hormone receptor superfamily, and they co-localize in the nucleus, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity, The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms KIAA0646
Properties 1 of the RNF8 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF8 Conjugated
Short name Conjugated, RNF8 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, RNF8 (Antibody to)
Alternative techniqueantibodies
Identity 10071
Gene RNF8
Long gene name ring finger protein 8
Synonyms gene name E3 ubiquitin protein ligase , ring finger protein (C3HC4 type) 8 ring finger protein 8 ring finger protein 8
Locus 6p21, 2
Discovery year 1999-09-29
GenBank acession AB012770
Entrez gene record 9025
Pubmed identfication 9734811 9852682
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000014620

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