Name : RNF8 Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4989583835
| Long name | Cy5 Conjugated, RNF8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | RNF8 |
| Specificity | This is a highly specific antibody against RNF8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human RNF8 |
| Gene ID number | 9025 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | It increases RXR?mediated transactivation of the RXR?responsive element (RXRE) promoter in a dose-dependent manner, It is required for the ubiquitination of some nuclear proteins and promotes their subsequent degradation, RNF8 also binds to Retinoid X receptor alpha (RXR?, RNF8 is a ubiquitously expressed nuclear RING finger protein that acts as an E3 ubiquitin-protein ligase, RNF8 may regulate mediation of UBC13 polyubiquitylation by elongating the ubiquitin chains, The heterodimeric ubiquitin-conjugating enzyme UBC13 interacts with RNF8, The ring finger protein (RNF) family includes any protein containing the signature RING finger motif, a member of the steroid hormone receptor superfamily, and they co-localize in the nucleus, suggesting that RNF8 is a regulator of RXR?mediated transcriptional activity, The RING finger motif is a specialized DNA-binding zinc finger domain found in many transcriptional regulatory proteins |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | KIAA0646 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RNF8 Conjugated |
| Short name | Conjugated, RNF8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, RNF8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 10071 |
| Gene | RNF8 |
| Long gene name | ring finger protein 8 |
| Synonyms gene name | E3 ubiquitin protein ligase , ring finger protein (C3HC4 type) 8 ring finger protein 8 ring finger protein 8 |
| Locus | 6p21, 2 |
| Discovery year | 1999-09-29 |
| GenBank acession | AB012770 |
| Entrez gene record | 9025 |
| Pubmed identfication | 9734811 9852682 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000014620 |