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ROBLD3 Antibody, ALEXA FLUOR 350

ROBLD3 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, ROBLD3 Polyclonal Antibody
Also known asAnti-ROBLD3 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenROBLD3
SpecificityThis is a highly specific antibody against ROBLD3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ROBLD3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetROBLD3
Short nameROBLD3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, ROBLD3 (Antibody to)
Alternative techniqueantibodies
Identity 29796
Gene LAMTOR2
Long gene name MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor
Synonyms gene ROBLD3
Synonyms gene name roadblock domain containing 3
Synonyms name mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein
Locus 1q22
Discovery year 2008-09-16
GenBank acession BC024190
Entrez gene record 28956
Pubmed identfication 11042152
RefSeq identity NM_014017
Classification Ragulator complex
Havana BLAST/BLAT OTTHUMG00000017462
Locus Specific Databases MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81

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