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ROBLD3 Antibody, Biotin Conjugated

ROBLD3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ROBLD3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenROBLD3
SpecificityThis is a highly specific antibody against ROBLD3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ROBLD3
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetROBLD3 Conjugated
Short name Conjugated, ROBLD3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ROBLD3 (Antibody to)
Alternative techniqueantibodies
Identity 29796
Gene LAMTOR2
Long gene name MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor
Synonyms gene ROBLD3
Synonyms gene name roadblock domain containing 3
Synonyms name mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein
Locus 1q22
Discovery year 2008-09-16
GenBank acession BC024190
Entrez gene record 28956
Pubmed identfication 11042152
RefSeq identity NM_014017
Classification Ragulator complex
Havana BLAST/BLAT OTTHUMG00000017462
Locus Specific Databases MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81

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