Name : ROBLD3 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7583891353
| Long name | Cy5, 5 Conjugated, ROBLD3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ROBLD3 |
| Specificity | This is a highly specific antibody against ROBLD3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ROBLD3 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | ROBLD3 Conjugated |
| Short name | Conjugated, ROBLD3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, ROBLD3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29796 |
| Gene | LAMTOR2 |
| Long gene name | MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor |
| Synonyms gene | ROBLD3 |
| Synonyms gene name | roadblock domain containing 3 |
| Synonyms name | mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein |
| Locus | 1q22 |
| Discovery year | 2008-09-16 |
| GenBank acession | BC024190 |
| Entrez gene record | 28956 |
| Pubmed identfication | 11042152 |
| RefSeq identity | NM_014017 |
| Classification | Ragulator complex |
| Havana BLAST/BLAT | OTTHUMG00000017462 |
| Locus Specific Databases | MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81 |