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Robo3 Antibody

Robo3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRobo3 Primary Polyclonal Antibody
Also known asRobo3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRobo3
SpecificityThis is a highly specific antibody against Robo3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Robo3
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Alternative transcript variants have been described but have not been experimentally validated, CC2, In mouse, Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS), ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily, ROBO3, ROBO3 lacks motif CC1, SLIT proteins 1-3, The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube, This gene, Unlike other ROBO family members, a family of secreted chemorepellants, a transmembrane segment, an autosomal recessive disorder characterized by congenital absence of horizontal gaze, and CC3 (CC for conserved cytoplasmic), and a cytoplasmic tail with three conserved signaling motifs: CC0, and axon fasciculation, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla, and vasculogenesis in addition to neurogenesis, angiogenesis, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, growth cone guidance, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, kidney morphogenesis, leukocyte migration, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain, progressive scoliosis, This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HGPS, RB inhibiting gene 1, ROBO3_HUMAN, Rbig 1, Rbig1, Retinoblastoma inhibiting gene 1, Rig 1, Rig1, Robo 3, Robo3, Robo3 protein, Roundabout, Roundabout axon guidance receptor homolog 3, Roundabout homolog 3, Roundabout like protein 3, Roundabout-like protein 3, axon guidance receptor, homolog 3 Drosophila, HGPPS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRobo3
Short nameRobo3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRobo3 (Antibody to)
Alternative techniqueantibodies
Identity 13433
Gene ROBO3
Long gene name roundabout guidance receptor 3
Synonyms gene HGPPS
Synonyms gene name Drosophila) homolog 3 horizontal gaze palsy with progressive scoliosis roundabout, axon guidance receptor, homolog 3 (Drosophila) , roundabout (axon guidance receptor
Synonyms RBIG1 FLJ21044 HGPS
Locus 11q24, 2
Discovery year 2004-05-10
GenBank acession AK024697
Entrez gene record 64221
Pubmed identfication 15105459
RefSeq identity XM_370663
Classification Fibronectin type III domain containing I-set domain containing Immunoglobulin like domain containing
Havana BLAST/BLAT OTTHUMG00000165934

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