| Long name | ROCK1(Thr455+Ser456) Primary Polyclonal Antibody |
| Also known as | ROCK1(Thr455+Ser456) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | SOD1 |
| Specificity | This is a highly specific antibody against SOD1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ROCK1 around the phosphorylation site of Thr455+Ser456 |
| Gene ID number | 6647 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Jul 2008], Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis, Rare transcript variants have been reported for this gene, The encoded isozyme is a soluble cytoplasmic protein, The other isozyme is a mitochondrial protein, [provided by RefSeq, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide, The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ROCK1_HUMAN, Renal carcinoma antigen NY REN 35, Rho associated coiled coil containing protein kinase 1, Rho associated protein kinase 1, Rho-associated coiled-coil containing protein kinase 1, p160 ROCK1, p160ROCK, p-ROCK1(Thr455/Ser456) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ROCK1(Thr455+Ser456) |
| Short name | ROCK1(Thr455+Ser456) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | coiled-coil containing protein kinase 1(Thr455+Ser456) (Antibody to), Rho-associated |
| Alternative technique | antibodies |
| Alternative to gene target | P160ROCK and ROCK-I, Plasma membranes, ROCK1 and IDBG-1371 and ENSG00000067900 and 6093, ROCK1 and IDBG-644080 and ENSBTAG00000008403 and 785911, Rock1 and IDBG-128359 and ENSMUSG00000024290 and 19877, coiled-coil containing protein kinase 1, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001726 and ruffle and cellular component this GO :0003383 and apical constriction and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005814 and centriole and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006939 and smooth muscle contraction and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0017048: Rho GTPase binding, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017048: Rho GTPase binding and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0017048 and Rho GTPase binding and molecular function this GO :0022614 and membrane to membrane docking and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0032059 and bleb and cellular component this GO :0032060 and bleb assembly and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0032970 and regulation of actin filament-based process and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045616 and regulation of keratinocyte differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0050901 and leukocyte tethering or rolling and biological process this GO :0051451 and myoblast migration and biological process this GO :0051492 and regulation of stress fiber assembly and biological process this GO :0051893 and regulation of focal adhesion assembly and biological process this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :2000114 and regulation of establishment of cell polarity and biological process this GO :2000145 and regulation of cell motility and biological process, Rho-associated |
| Identity | 10251 |
| Gene | ROCK1 |
| Long gene name | Rho associated coiled-coil containing protein kinase 1 |
| Synonyms | p160ROCK |
| Locus | 18q11, 1 |
| Discovery year | 1997-10-10 |
| Entrez gene record | 6093 |
| Pubmed identfication | 8617235 |
| RefSeq identity | NM_005406 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000131723 |
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