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Ron (Tyr1238+Tyr1239) Antibody, ALEXA FLUOR 647

Ron (Tyr1238+Tyr1239) Antibody, ALEXA FLUOR 647 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, Ron (Tyr1238+Tyr1239) Antibody
Also known asAnti-Ron Tyr1238+Tyr1239 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRon Tyr1238+Tyr1239
SpecificityThis is a highly specific antibody against Ron Tyr1238+Tyr1239
ModificationPhosphorylation
Modification SiteTyr1238+Tyr1239
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1235-1245/1400
Subcellular locationCell membrane
SourceKLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238+Tyr1239
Gene ID Number4486
Swiss ProtQ04912
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Alternatively, Following activation by ligand, Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules, PI3 kinase-AKT, PLCG1 or the adapter GAB1, Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand, RON signaling activates the wound healing response by promoting epithelial cell migration, Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including cell survival, interacts with the PI3-kinase subunit PIK3R1, migration and differentiation, or PLCgamma-PKC, proliferation as well as survival at the wound site, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms CD136, CDw136, MSP receptor, MST1R, Macrophage-stimulating protein receptor, PTK8, Protein-tyrosine kinase 8, p185-Ron, RON
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Ron (Tyr1238+Tyr1239) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetRon (Tyr1238+Tyr1239)
Short nameRon (Tyr1238+Tyr1239) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, Ron (Tyr1238+Tyr1239) (Antibody to)
Alternative techniqueantibodies

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