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RORG Antibody, ALEXA FLUOR 350

RORG Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, RORG Polyclonal Antibody
Also known asAnti-RORG PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenRORG
SpecificityThis is a highly specific antibody against RORG
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range440-490/518
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RORG
Gene ID Number6097
Swiss ProtP51449
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ARNTL/BMAL1 and NR1D1 in peripheral tissues and in a tissue-selective manner, CRY1 and NR1D1 itself, Competes with NR1D1 for binding to their shared DNA response element on some clock genes such as ARNTL/BMAL1, Considered to have intrinsic transcriptional activity, Controls adipogenesis as well as adipocyte size and modulates insulin sensitivity in obesity, In liver, Involved in the regulation of the rhythmic expression of genes involved in glucose and lipid metabolism, Key regulator of cellular differentiation, Negative regulator of adipocyte differentiation through the regulation of early phase genes expression, Recruits distinct combinations of cofactors to target gene regulatory regions to modulate their transcriptional expression, Regulates the circadian expression of clock genes such as CRY1, Therefore influences the period length and stability of the clock, depending on the tissue, enhancing or repressing the transcriptional activity, has specific and redundant functions with RORA as positive or negative modulator of expression of genes encoding phase I and Phase II proteins involved in the metabolism of lipids, have some natural ligands like oxysterols that act as agonists (25-hydroxycholesterol) or inverse agonists (7-oxygenated sterols), immunity, including PLIN2 and AVPR1A, leading to the circadian pattern of clock genes expression, peripheral circadian rhythm as well as lipid, respectively, resulting in NR1D1-mediated repression or RORC-mediated activation of the expression, steroid, steroids and xenobiotics, such as MMP3, such as SULT1E1, time and promoter contexts, xenobiotics and glucose metabolism, Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms RZRG RORG NR1F3 TOR
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetRORG
Short nameRORG Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, RORG (Antibody to)
Alternative techniqueantibodies
Identity 10260
Gene RORC
Long gene name RAR related orphan receptor C
Synonyms gene name RAR-related orphan receptor C
Locus 1q21
Discovery year 1995-04-13
GenBank acession U16997
Pubmed identfication 7811290
Classification Nuclear hormone receptors
Havana BLAST/BLAT OTTHUMG00000013053

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